Carla V Rothlin Selected Research

c-Mer Tyrosine Kinase

2/2023	Single-cell transcriptomic atlas of Alzheimer's disease middle temporal gyrus reveals region, cell type and sex specificity of gene expression with novel genetic risk for MERTK in female.
1/2023	Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa.
1/2022	Tissue-specific modifier alleles determine Mertk loss-of-function traits.
1/2022	Phosphatidylserine Synthase PTDSS1 Shapes the Tumor Lipidome to Maintain Tumor-Promoting Inflammation.
1/2021	Macrophage AXL receptor tyrosine kinase inflames the heart after reperfused myocardial infarction.
10/2020	A Network of Macrophages Supports Mitochondrial Homeostasis in the Heart.
1/2020	Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.
12/2019	Funerals and Feasts: The Immunological Rites of Cell Death.
1/2018	Erythrocyte efferocytosis modulates macrophages towards recovery after intracerebral hemorrhage.
10/2017	Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation.

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Carla V Rothlin Research Topics

Disease

13	Inflammation (Inflammations) 01/2023 - 08/2006
8	Neoplasms (Cancer) 01/2022 - 08/2013
5	Infections 01/2017 - 08/2013
2	Alzheimer Disease (Alzheimer's Disease) 02/2023 - 01/2023
2	Fibrosis (Cirrhosis) 01/2022 - 01/2020
2	Zika Virus Infection 10/2021 - 01/2017
2	Liver Cirrhosis (Hepatic Cirrhosis) 01/2020 - 09/2015
2	Colitis-Associated Neoplasms 01/2017 - 08/2014
1	Intestinal Diseases (Diseases, Intestinal) 11/2023
1	Cadaver (Cadavers) 05/2023
1	Neurodegenerative Diseases (Neurodegenerative Disease) 02/2023
1	Neuroinflammatory Diseases 02/2023
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2023
1	Breast Neoplasms (Breast Cancer) 01/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Melanoma (Melanoma, Malignant) 01/2022
1	Retinal Degeneration 01/2022
1	Leukemia 11/2021
1	Hypoxia (Hypoxemia) 01/2021
1	Myocardial Infarction 01/2021
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Infarction (Infarctions) 01/2021
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2021
1	Ventricular Dysfunction 10/2020
1	Non-alcoholic Fatty Liver Disease 01/2020
1	Lung Neoplasms (Lung Cancer) 01/2020
1	Hematoma 01/2018
1	Pregnancy Complications 01/2018
1	Virus Diseases (Viral Diseases) 10/2017
1	Colorectal Neoplasms (Colorectal Cancer) 01/2017
1	Parasitic Diseases (Parasitic Disease) 02/2016
1	Asthma (Bronchial Asthma) 02/2016
1	Carcinogenesis 09/2015
1	Glioblastoma (Glioblastoma Multiforme) 08/2014
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2014
1	Colonic Neoplasms (Colon Cancer) 08/2013
1	Colitis 07/2013
1	Tuberous Sclerosis (Bourneville's Disease) 09/2006

Drug/Important Bio-Agent (IBA)

14	c-Mer Tyrosine KinaseIBA 02/2023 - 08/2014
9	Phosphotransferases (Kinase)IBA 12/2019 - 08/2013
7	CytokinesIBA 01/2021 - 12/2007
7	tyrosine receptor (receptor, tyrosine)IBA 12/2019 - 08/2013
5	LigandsIBA 11/2021 - 08/2013
3	InflammasomesIBA 10/2020 - 10/2017
3	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2017 - 08/2014
2	RNA (Ribonucleic Acid)IBA 02/2023 - 01/2020
2	Immune Checkpoint InhibitorsIBA 01/2022 - 01/2017
2	AntibodiesIBA 01/2022 - 08/2013
2	Axl Receptor Tyrosine KinaseIBA 11/2021 - 01/2021
2	AntigensIBA 01/2020 - 07/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2014 - 08/2006
1	LipidsIBA 05/2023
1	RetinoidsIBA 05/2023
1	Amyloid (Amyloid Fibrils)IBA 02/2023
1	DNA (Deoxyribonucleic Acid)IBA 01/2023
1	ruxolitinibIBA 01/2023
1	Ether (Diethyl Ether)IBA 01/2022
1	FlavoproteinsIBA 01/2022
1	CDPdiacylglycerol-Serine O-PhosphatidyltransferaseIBA 01/2022
1	PhosphatidylserinesIBA 01/2022
1	Platelet-Derived Growth FactorIBA 01/2022
1	Retinal Pigments (Pigments, Visual)IBA 01/2022
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022
1	renalaseIBA 01/2022
1	Programmed Cell Death 1 ReceptorIBA 01/2022
1	Metalloproteases (Metalloproteinases)IBA 01/2020
1	IronIBA 01/2018
1	Antiphospholipid AntibodiesIBA 01/2018
1	LipopolysaccharidesIBA 10/2017
1	Interleukin-4 (Interleukin 4)IBA 01/2017
1	InterferonsIBA 01/2017
1	AllergensIBA 02/2016
1	Antiviral Agents (Antivirals)IBA 01/2016
1	bemcentinibIBA 09/2015
1	CollagenIBA 09/2015
1	ErbB Receptors (EGF Receptor)IBA 08/2014
1	Transcription Factors (Transcription Factor)IBA 08/2014
1	PKC-3 proteinIBA 08/2014
1	Dextran SulfateIBA 08/2013
1	AzoxymethaneIBA 08/2013
1	Toll-Like Receptors (Toll-Like Receptor)IBA 12/2010
1	Interferon Type IIBA 12/2010
1	STAT1 Transcription FactorIBA 12/2007
1	Interferon alpha-beta Receptor (Receptor, Interferon alpha beta)IBA 12/2007
1	NF-kappa B (NF-kB)IBA 09/2006

Therapy/Procedure

8	Therapeutics 11/2023 - 08/2013
3	Immunotherapy 11/2021 - 01/2017